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Cipro (Ciprofloxacin)

Cipro is an antibiotic fluoroquinolone. It is an antimicrobial agent for systemic use. The drug inhibits the growth of pathogens that cause infectious diseases.

Table of Contents

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What is it?

Cipro is an antibiotic. One tablet contains the active ingredient: ciprofloxacin – 250 mg or 500 mg; additional substances are povidone, colloidal anhydrous silicon dioxide, talc, croscarmellose sodium, corn starch, magnesium stearate, opadry II (contains – polyvinyl alcohol, talc, macrogol 3350, lecithin, titanium dioxide).

What is it used for?

Infections caused by vulnerable to the medication microorganisms are:

  • lower respiratory tract infections caused by gram-negative bacteria (pneumonia, except pneumococcal, bronchopulmonary infections in chronic obstructive pulmonary disease, cystic fibrosis, bronchiectasis);
  • infections of the middle ear and paranasal sinuses caused by gram-negative bacteria;
  • infections of the kidneys and urinary tract;
  • skin and soft tissue infections caused by gram-negative bacteria;
  • infections of bones and joints;
  • pelvic infection (including adnexitis and prostatitis);
  • gonorrhea;
  • gastrointestinal infections (including diarrhea caused by enterotoxigenic strains of E. coli, Campylobacter jejuni);
  • intra-abdominal infections;
  • infections in patients with reduced immunity (with neutropenia).

Cipro - Antibiotic with A Wide Spectrum of Action

How to take it?

Prescribed for oral application, regardless of the meal, not chewing, washing down with water. When used on an empty stomach, the absorption of ciprofloxacin is increased. Foods high in calcium (milk, yogurt) can reduce the absorption of ciprofloxacin.

The dose of ciprofloxacin depends on the type and severity of the infection, the age, body weight and the functional state of the kidneys.

The duration of treatment depends on disease severity, the clinical and bacteriological response. In general, treatment should be continued for at least 3 days after normalization of body temperature or resolution of clinical symptoms.

What to avoid when taking it?

You should not take Cipro in the case of allergies to ciprofloxacin, other quinolones, excipients of this medication, as well as the simultaneous use of tizanidine.

Main contraindications are:

  • pseudomembranous colitis;
  • pregnancy;
  • lactation period;
  • children and adolescents up to 18 years;
  • hypersensitivity to ciprofloxacin or other drugs from the group of fluoroquinolones.

Be careful if you suffer from:

  • pronounced atherosclerosis of cerebral vessels;
  • impaired cerebral circulation;
  • mental illness;
  • epileptic syndrome;
  • epilepsy;
  • severe renal and/or hepatic insufficiency;
  • old age.

Side effects

  • Frequent side effects of Cipro (1 in 10–100 cases): loose stools, nausea.
  • Infrequent negative reactions (1 per 100–1000 cases): eosinophilia, fungal superinfection, lack of appetite, hyperactivity, headaches, taste disturbances, dizziness, sleep disorders, vomiting, flatulence, pain in the stomach/intestine, increased liver enzymes, itching, increased bilirubin, musculoskeletal pain, rash, urticaria, kidney dysfunction, fever, fatigue.
  • Rare side effects (1 in 1–10 thousand cases): changes in the number of leukocytes, anemia, decreased platelet rate, sugar levels, allergic reactions, confusion, depression with the appearance of suicidal thoughts, pathological dreams, changes in sensitivity , dizziness, trembling, convulsions, impaired vision, lowering blood pressure, hearing disorders, tachycardia, fainting, disorders of the liver, asphyxiation, jaundice, hepatitis, muscle pain, sun intolerance light (photosensitivity), joints’ inflammation, muscle cramps, increased muscle tone, kidney failure, nephritis, blood/crystals in the urine, increased amylase activity.
  • Very rare reactions (frequency of disorders not known): an increase in prothrombin time, peripheral neuropathy, arrhythmia, ventricular tachycardia, acute pustular exanthema.

How long do side effects last?

The duration of side effects depends on the individual characteristics. It is necessary to consult a doctor if you feel unpleasant effects from Cipro. In many cases, the side effects disappear after your body gets used to the main component of this antibiotic.


Indications for use Single/daily dose The treatment duration
Infections of lower respiratory tract 500-750 mg

2 times a day

7-14 days
Infections of the upper respiratory tract Chronic sinusitis exacerbations 500-750 mg

2 times a day

7-14 days
Chronic othelcosis 500-750 mg

2 times a day

7-14 days
Malignant otitis externa 750 mg

2 times a day

28 days- 3 months
Genital urinary tract infections Non-complicate cystitis 250-500 mg

2 times a day

3 days
Complicated cystitis, non-complicated pyelonephritis 500 mg
2 times a day
7 days
Complicated pyelonephritis 500-750 mg
2 times a day
No more than 10 days, some cases require up to 21 days course
Prostatitis 500-750 mg

2 times a day

2-4 weeks (acute)

4-6 weeks (chronic)

Genital infections gonococcal urethritis and cervicitis Single dose – 500 mg Single dose
Epididymoorchitis and pelvic inflammatory diseases 500-750 mg

2 times a day

No more than 14 days
Digestive tract infections and intraabdominal infections Diarrhea, caused by bacterial infection, including Shigella spp, except for Shigella dysenteriae of the I type 500 mg

2 times a day

1 day
Diarrhea, caused by Shigella dysenteriae of the I type 500 mg

2 times a day

5 days
Diarrhea, caused by Vibrio cholera 500 mg

2 times a day

3 days
Typhoid fever 500 mg

2 times a day

7 days
Intraabdominal infection caused gram-negative microorganisms 250-500 mg

2 times a day

5-14 days
Skin and subcutaneous infections 250-500 mg

2 times a day

7-14 days
Infections of joints 250-500 mg

2 times a day

max. 3 months
Profilaxis and the treatment of infections in patients with neutropenia 500-750 mg

2 times a day

Therapy is going on until the end of neutropenia
Profilaxis of invasive infections, caused by Neisseria meningitides 500 mg Single dose
Postexposure prophylaxis and treatment of malignant carbuncle. Combined therapy 500 mg

2 times a day

60 days from the moment of catching an infection

Cipro and alcohol

What can happen if, during the antibiotic treatment, take a shot or two of strong alcohol? Perhaps the patient will not have any external symptoms indicating any intoxication, but at the same time, the internal organs will take a real burden.

Alcohol and Cipro are likewise metabolized in the liver and excreted by the kidneys, therefore, these vital organs will be detoxified by both substances.

Before taking any dose of alcohol during the course of treatment, it is worth remembering that such a combination, as a rule, increases the manifestations of side effects from the drug.